Ceramide AP

Ceramide AP — formerly ceramide 6 — is a phytosphingosine-based ceramide that anchors the corneocyte lipid envelope and keeps the stratum corneum’s lamellar sheets organised. In barrier-repair formulations it works synergistically with ceramide NP, cholesterol, and free fatty acids; clinical research on atopic dermatitis shows the combination reduces TEWL, itching, and irritation. Ceramide AP is particularly valued in post-peel, post-retinoid, and eczema-support routines where the barrier is actively compromised. Typical use levels sit at 0.05–0.5% — small molecule, big effect. Look for it paired with its siblings in a "ceramide complex" rather than alone for the strongest lamellar reconstruction.